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nivolumab and ipilimumab medications led to a reduction in the size of tumours in terminally ill head and neck cancer patients

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  • nivolumab and ipilimumab medications led to a reduction in the size of tumours in terminally ill head and neck cancer patients

    https://www.theguardian.com/society/...ll-finds-trial

    Interesting to see more results, as this is what my daughter tried for her DIPG. The trial results weren't positive, but I can honestly say that while she was on the two medicines it help keep the DIPG at bay. Both MSKCC and Yale thought it was holding back the growth.

    I would have loved to have tried adding on an inhibitor while keeping those two immunotherpies.

  • #2
    How bad was taking it? One of my friends tried that combination and had some really bad side effects.

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    • #3
      She had nothing. She had some mild allergic reaction in the beginning, but we started her on a daily regiment of Zyrtec and after that she was fine.

      Once she overcame all the side effects of Dexamethasone she lead a completely normal life, until the MRI showed the tumor had started growing again.
      Last edited by davidfinn; 10-13-2021, 05:50 PM.

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      • #4
        I wonder what kind of trial was performed? A case serial? At first glance, I'm not sure the outcomes are accurate and statistically significant. At least, it's a good terrain for other studies to be performed. By the way, I encountered here with mc38 cell line developed artificially in mice that allows studying in vitro the effectiveness of immunotherapies drugs. I suppose that gives us the opportunity of gathering more information before starting clinical trials on humans. I understand well that trials on humans are a superior step; nevertheless, I'm not sure the rush is worth it.
        Last edited by dixiemcgahee57; 04-29-2022, 08:37 AM.

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